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  1. Bog
  2. Præklinisk medicin: basale fag
  3. Medicinsk genetik

The Secret Lives of Transcription Factors

- In Heterochromatin Regulation
Af: Willis X. Li, Louise Silver-Morse Engelsk Paperback

The Secret Lives of Transcription Factors

- In Heterochromatin Regulation
Af: Willis X. Li, Louise Silver-Morse Engelsk Paperback
Tjek vores konkurrenters priser
This SpringerBrief explores unconventional functions of eight different transcription factors and concludes with a discussion of their biological significance and impact, including effects on processes within the cell nucleaus during development and in adult organisms. Chapter One details unconventional functions of the transcription factors  GAGA, HP1, Rb, STAT, ATF-2 and NF-kB.  Surprisingly, all of these transcription factors can be found in association with heterochromatin as well as euchromatin, and in some cases unconventional functions have been demonstrated for these heterochromatin-associated factors. Chapter Two focuses on the unconventional functions of STAT and HP1 and discusses their roles in the promotion of longevity, and in protection from cancer and DNA damage.  Chapter Three explores the biological significance of the findings presented in the first two chapters and considers how global changes in the epigenome brought about by factors such as STAT and HP1 might affect processes within the cell nucleus during development and in adult organisms. This succinct yet thorough SpringerBrief is essential for researchers studying epigenetics, and to instructors of the subject.  It should also appeal to people interested in the control of gene transcription and other processes in the cell nucleus, and to those interested in development.
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This SpringerBrief explores unconventional functions of eight different transcription factors and concludes with a discussion of their biological significance and impact, including effects on processes within the cell nucleaus during development and in adult organisms. Chapter One details unconventional functions of the transcription factors  GAGA, HP1, Rb, STAT, ATF-2 and NF-kB.  Surprisingly, all of these transcription factors can be found in association with heterochromatin as well as euchromatin, and in some cases unconventional functions have been demonstrated for these heterochromatin-associated factors. Chapter Two focuses on the unconventional functions of STAT and HP1 and discusses their roles in the promotion of longevity, and in protection from cancer and DNA damage.  Chapter Three explores the biological significance of the findings presented in the first two chapters and considers how global changes in the epigenome brought about by factors such as STAT and HP1 might affect processes within the cell nucleus during development and in adult organisms. This succinct yet thorough SpringerBrief is essential for researchers studying epigenetics, and to instructors of the subject.  It should also appeal to people interested in the control of gene transcription and other processes in the cell nucleus, and to those interested in development.
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Se mere i:
Produktdetaljer
Sprog: Engelsk
Sider: 45
ISBN-13: 9783031290275
Indbinding: Paperback
Udgave:
ISBN-10: 3031290275
Kategori: Medicinsk genetik
Udg. Dato: 26 apr 2023
Længde: 0mm
Bredde: 155mm
Højde: 235mm
Forlag: Springer International Publishing AG
Oplagsdato: 26 apr 2023
Forfatter(e): Willis X. Li, Louise Silver-Morse
Forfatter(e) Willis X. Li, Louise Silver-Morse

Kategori Medicinsk genetik

ISBN-13 9783031290275

Sprog Engelsk

Indbinding Paperback

Sider 45

Udgave

Længde 0mm

Bredde 155mm

Højde 235mm

Udg. Dato 26 apr 2023

Oplagsdato 26 apr 2023

Forlag Springer International Publishing AG

Kategori sammenhænge