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Structural and Mediator Lipidomics

- A Functional View
Af: Michel Lagarde, Celine Costaz, Michel Guichardant, Nathalie Bernoud-Hubac, Frederic Carriere Engelsk Hardback

Structural and Mediator Lipidomics

- A Functional View
Af: Michel Lagarde, Celine Costaz, Michel Guichardant, Nathalie Bernoud-Hubac, Frederic Carriere Engelsk Hardback
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Lipidomics forms part of the field of metabolomics, which in turn follows on from genomics, transcriptomics, and proteomics, in a top-down manner. It is the study of hydrophobic molecules called lipids; however, lipid molecular species are so numerous that investigators tend to subdivide global lipidomics into targeted lipidomic approaches. This book focuses on structural and mediator lipidomics, with a particular emphasis on their functional aspects. This includes lipids deserving of special interest for their structures (especially as parts of cell membranes or plasma lipoprotein particles) and lipids known for their biological activities, which mediate the action of cell agonists (for example, hormones, growth factors, etc.). The oxygenated metabolites of the major functional w6 and w3 polyunsaturated fatty acids in mammals, in particular arachidonic and docosahexaenoic acids, are presented, with special attention paid to their structure-function relationships. These metabolites are very active, and their biological relevance was recognized early on with a Nobel Prize in Physiology and Medicine in 1982. Finally, general principles for the high performance analysis and characterization of lipid species are also presented. The book has been written for undergraduate students and scientists interested in the field of lipids. Clinicians will also be able to find useful information, due to the numerous references to pathophysiology.
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Lipidomics forms part of the field of metabolomics, which in turn follows on from genomics, transcriptomics, and proteomics, in a top-down manner. It is the study of hydrophobic molecules called lipids; however, lipid molecular species are so numerous that investigators tend to subdivide global lipidomics into targeted lipidomic approaches. This book focuses on structural and mediator lipidomics, with a particular emphasis on their functional aspects. This includes lipids deserving of special interest for their structures (especially as parts of cell membranes or plasma lipoprotein particles) and lipids known for their biological activities, which mediate the action of cell agonists (for example, hormones, growth factors, etc.). The oxygenated metabolites of the major functional w6 and w3 polyunsaturated fatty acids in mammals, in particular arachidonic and docosahexaenoic acids, are presented, with special attention paid to their structure-function relationships. These metabolites are very active, and their biological relevance was recognized early on with a Nobel Prize in Physiology and Medicine in 1982. Finally, general principles for the high performance analysis and characterization of lipid species are also presented. The book has been written for undergraduate students and scientists interested in the field of lipids. Clinicians will also be able to find useful information, due to the numerous references to pathophysiology.
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Se mere i:
Produktdetaljer
Sprog: Engelsk
Sider: 108
ISBN-13: 9782940222926
Indbinding: Hardback
Udgave:
ISBN-10: 2940222924
Kategori: Biokemi
Udg. Dato: 13 jun 2016
Længde: 18mm
Bredde: 251mm
Højde: 170mm
Forlag: Presses Polytechniques et Universitaires Romandes
Oplagsdato: 13 jun 2016
Forfatter(e): Michel Lagarde, Celine Costaz, Michel Guichardant, Nathalie Bernoud-Hubac, Frederic Carriere
Forfatter(e) Michel Lagarde, Celine Costaz, Michel Guichardant, Nathalie Bernoud-Hubac, Frederic Carriere

Kategori Biokemi

ISBN-13 9782940222926

Sprog Engelsk

Indbinding Hardback

Sider 108

Udgave

Længde 18mm

Bredde 251mm

Højde 170mm

Udg. Dato 13 jun 2016

Oplagsdato 13 jun 2016

Forlag Presses Polytechniques et Universitaires Romandes