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Bioinformatics and Genome Analysis

Engelsk Paperback

Bioinformatics and Genome Analysis

Engelsk Paperback
Tjek vores konkurrenters priser
Bioinformatics is emerging as a field with ever-increasing promise, ur- gency, and necessity. All three of these facets can be seen in the con- text of the recent sequencing of the human genome. The creation of a novel algorithm for the assembly of whole genome shotgun data sets accelerated the project and resulted in its near completion in 2001. The urgency became apparent with the landslide of data that ensued and the realization that current databases and tool sets are not up to the task. Finally, the necessity of bioinformatics as a facet of molecular biologi- cal research becomes evident in the impossibility of individual human comprehension of all the details of the functioning of a cell at the mo- lecular level, especially now that we stand on the edge of this preci- pice. We find ourselves at a time when we have the essentially complete genomes of human and mouse, and the completed sequences of Droso- phila melanogaster, Caenorhabditis elegans, several fungi including Saccharomyces cerevisiae, and many bacteria including Escherichia coli. There are volumes of mRNA expression data sets, high-density maps of highly variable SNPs for both human and mouse, physical marker maps for many other important agricultural and drug trial ani- mals, and a complete knock-out survey of yeast. In addition, the se- quencing of D. pseudoobscura and Caenorhabditis briggsae in the near future will provide unusual comparative genomic insights.
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Bioinformatics is emerging as a field with ever-increasing promise, ur- gency, and necessity. All three of these facets can be seen in the con- text of the recent sequencing of the human genome. The creation of a novel algorithm for the assembly of whole genome shotgun data sets accelerated the project and resulted in its near completion in 2001. The urgency became apparent with the landslide of data that ensued and the realization that current databases and tool sets are not up to the task. Finally, the necessity of bioinformatics as a facet of molecular biologi- cal research becomes evident in the impossibility of individual human comprehension of all the details of the functioning of a cell at the mo- lecular level, especially now that we stand on the edge of this preci- pice. We find ourselves at a time when we have the essentially complete genomes of human and mouse, and the completed sequences of Droso- phila melanogaster, Caenorhabditis elegans, several fungi including Saccharomyces cerevisiae, and many bacteria including Escherichia coli. There are volumes of mRNA expression data sets, high-density maps of highly variable SNPs for both human and mouse, physical marker maps for many other important agricultural and drug trial ani- mals, and a complete knock-out survey of yeast. In addition, the se- quencing of D. pseudoobscura and Caenorhabditis briggsae in the near future will provide unusual comparative genomic insights.
Produktdetaljer
Sprog: Engelsk
Sider: 300
ISBN-13: 9783662047491
Indbinding: Paperback
Udgave:
ISBN-10: 3662047497
Kategori: Medicinsk genetik
Udg. Dato: 26 dec 2012
Længde: 0mm
Bredde: 0mm
Højde: 0mm
Forlag: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Oplagsdato: 26 dec 2012
Forfatter(e):
Forfatter(e)


Kategori Medicinsk genetik


ISBN-13 9783662047491


Sprog Engelsk


Indbinding Paperback


Sider 300


Udgave


Længde 0mm


Bredde 0mm


Højde 0mm


Udg. Dato 26 dec 2012


Oplagsdato 26 dec 2012


Forlag Springer-Verlag Berlin and Heidelberg GmbH & Co. KG

Kategori sammenhænge