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  3. Farmaceutisk kemi og teknologi

G Protein-Coupled Receptors

- Immobilization and Applications in Drug Discovery
Af: Xinfeng Zhao, Qian Li, Qi Liang, Jing Wang, Jia Quan Engelsk Paperback

G Protein-Coupled Receptors

- Immobilization and Applications in Drug Discovery
Af: Xinfeng Zhao, Qian Li, Qi Liang, Jing Wang, Jia Quan Engelsk Paperback
Tjek vores konkurrenters priser
This book summarizes the progress made to functional immobilize G protein-coupled receptors (GPCRs) through site-specific or orientated recognition in both non-covalent and covalent manners. The last decade is the dawn of the "post-structural biology" era for G protein-coupled receptor research. As an emerging approach for state-of-the-art immobilization, this book discusses efforts to explore the elegance of naturally-occurring biochemical reactions by using their high specificity and robust reactivity in the complex system, such as site-specific conjugation by covalent recognition between enzymes and their substrates. With the perspective of protein-drug interactions, this book also reviews the applications of protein immobilization, with an emphasis on G protein-coupled receptors, in drug discovery and protein-ligand interaction analysis. In addition, the merits, opportunities and disadvantages are analyzed for different immobilization methods, and a perspective for future directions is presented. Given its scope, this book appeals to a broad readership, particularly researchers engaged in the field of analytical chemistry, bioconjugate chemistry, and chemical biology, and other related field, as well as teachers of relevant majors in colleges and universities.
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This book summarizes the progress made to functional immobilize G protein-coupled receptors (GPCRs) through site-specific or orientated recognition in both non-covalent and covalent manners. The last decade is the dawn of the "post-structural biology" era for G protein-coupled receptor research. As an emerging approach for state-of-the-art immobilization, this book discusses efforts to explore the elegance of naturally-occurring biochemical reactions by using their high specificity and robust reactivity in the complex system, such as site-specific conjugation by covalent recognition between enzymes and their substrates. With the perspective of protein-drug interactions, this book also reviews the applications of protein immobilization, with an emphasis on G protein-coupled receptors, in drug discovery and protein-ligand interaction analysis. In addition, the merits, opportunities and disadvantages are analyzed for different immobilization methods, and a perspective for future directions is presented. Given its scope, this book appeals to a broad readership, particularly researchers engaged in the field of analytical chemistry, bioconjugate chemistry, and chemical biology, and other related field, as well as teachers of relevant majors in colleges and universities.
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Produktdetaljer
Sprog: Engelsk
Sider: 91
ISBN-13: 9789819900770
Indbinding: Paperback
Udgave:
ISBN-10: 9819900778
Kategori: Farmaceutisk kemi og teknologi
Udg. Dato: 21 feb 2023
Længde: 0mm
Bredde: 155mm
Højde: 235mm
Forlag: Springer Verlag, Singapore
Oplagsdato: 21 feb 2023
Forfatter(e): Xinfeng Zhao, Qian Li, Qi Liang, Jing Wang, Jia Quan
Forfatter(e) Xinfeng Zhao, Qian Li, Qi Liang, Jing Wang, Jia Quan

Kategori Farmaceutisk kemi og teknologi

ISBN-13 9789819900770

Sprog Engelsk

Indbinding Paperback

Sider 91

Udgave

Længde 0mm

Bredde 155mm

Højde 235mm

Udg. Dato 21 feb 2023

Oplagsdato 21 feb 2023

Forlag Springer Verlag, Singapore

Kategori sammenhænge