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Chromosome Architecture

- Methods and Protocols
Engelsk Paperback

Chromosome Architecture

- Methods and Protocols
Engelsk Paperback
Tjek vores konkurrenters priser
This detailed new edition collects cutting-edge laboratory protocols, techniques, and applications in use by some of the leading international experts in the broad field of chromosome architecture. The book emphasizes the increasing physiological relevance of chromosome architecture investigation, manifest both through application of more complex bottom-up assays in vitro as well as through maintaining the native physiological context through the investigation of living, functional cells. In addition, the chapters reflect the dramatic improvement in the length scale of precision by utilizing single-molecule approaches, both for imaging the DNA content of chromosome and proteins that bind to DNA as well as using methods that can controllably manipulate single DNA molecules, and the use of advanced computational methods and mathematical analysis is also featured. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Chromosome Architecture: Methods and Protocols, Second Edition is an ideal guide for researchers working in this dynamic area of study.
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This detailed new edition collects cutting-edge laboratory protocols, techniques, and applications in use by some of the leading international experts in the broad field of chromosome architecture. The book emphasizes the increasing physiological relevance of chromosome architecture investigation, manifest both through application of more complex bottom-up assays in vitro as well as through maintaining the native physiological context through the investigation of living, functional cells. In addition, the chapters reflect the dramatic improvement in the length scale of precision by utilizing single-molecule approaches, both for imaging the DNA content of chromosome and proteins that bind to DNA as well as using methods that can controllably manipulate single DNA molecules, and the use of advanced computational methods and mathematical analysis is also featured. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Chromosome Architecture: Methods and Protocols, Second Edition is an ideal guide for researchers working in this dynamic area of study.
Produktdetaljer
Sprog: Engelsk
Sider: 330
ISBN-13: 9781071622230
Indbinding: Paperback
Udgave:
ISBN-10: 1071622234
Udg. Dato: 1 jun 2023
Længde: 0mm
Bredde: 178mm
Højde: 254mm
Forlag: Springer-Verlag New York Inc.
Oplagsdato: 1 jun 2023
Forfatter(e):
Forfatter(e)


Kategori Cellebiologi (cytologi)


ISBN-13 9781071622230


Sprog Engelsk


Indbinding Paperback


Sider 330


Udgave


Længde 0mm


Bredde 178mm


Højde 254mm


Udg. Dato 1 jun 2023


Oplagsdato 1 jun 2023


Forlag Springer-Verlag New York Inc.