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Advances in biomedical NMR with spatial resolution

Af: Dr Jennifer Flohr Engelsk Paperback

Advances in biomedical NMR with spatial resolution

Af: Dr Jennifer Flohr Engelsk Paperback
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In modern medicine, magnetic resonance imaging (MRI) is an essential diagnostic tool, which enables physicians to detect a great variety of diseases and physical injuries. The scope of possibilities encompasses neuro-, cardiovascular-, musculoskeletal-, hepatobiliary- and gastrointestinal imaging as well a magnetic resonance angiography. Besides commercially available MRI scanners, low magnetic field devices gain more and more attention because they are more compact, mostly portable, easier to handle due to the lack of cryogenic coolants, and usually come with a large cost saving.

In this thesis, high magnetic field devices and unilateral NMR sensors are deployed to explore different biomedical topics. Imaging techniques are used to study the flow inside aneurysms—enlargements of blood vessels in the human body, whose rupture can lead to severe health issues. In an experimental flow set-up, different fluids and flow velocities are tested inside silicon aneurysm models with and without stents. These narrow tubes, which commonly consist of a metallic network, are inserted into a vessel to cut the aneurysm from the blood stream.

TheNMR-MOUSER (MObileUniversal Surface Explorer), a sensor design first conceived in the mid 90s by Blümich and Blümler, and its derivative — the Fourier NMR-MOUSE — are utilized to study human and porcine skin. Outer skin layers are investigated in terms of diffusion and relaxation time profiling in laboratory and clinical studies. They assess the structural composition and susceptibility to different substances, and identify carcinogenic processes and the effect of aging and renal insufficiency.

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In modern medicine, magnetic resonance imaging (MRI) is an essential diagnostic tool, which enables physicians to detect a great variety of diseases and physical injuries. The scope of possibilities encompasses neuro-, cardiovascular-, musculoskeletal-, hepatobiliary- and gastrointestinal imaging as well a magnetic resonance angiography. Besides commercially available MRI scanners, low magnetic field devices gain more and more attention because they are more compact, mostly portable, easier to handle due to the lack of cryogenic coolants, and usually come with a large cost saving.

In this thesis, high magnetic field devices and unilateral NMR sensors are deployed to explore different biomedical topics. Imaging techniques are used to study the flow inside aneurysms—enlargements of blood vessels in the human body, whose rupture can lead to severe health issues. In an experimental flow set-up, different fluids and flow velocities are tested inside silicon aneurysm models with and without stents. These narrow tubes, which commonly consist of a metallic network, are inserted into a vessel to cut the aneurysm from the blood stream.

TheNMR-MOUSER (MObileUniversal Surface Explorer), a sensor design first conceived in the mid 90s by Blümich and Blümler, and its derivative — the Fourier NMR-MOUSE — are utilized to study human and porcine skin. Outer skin layers are investigated in terms of diffusion and relaxation time profiling in laboratory and clinical studies. They assess the structural composition and susceptibility to different substances, and identify carcinogenic processes and the effect of aging and renal insufficiency.

Produktdetaljer
Sprog: Engelsk
Sider: 158
ISBN-13: 9783958862869
Indbinding: Paperback
Udgave:
ISBN-10: 3958862861
Udg. Dato: 24 maj 2019
Længde: 11mm
Bredde: 149mm
Højde: 210mm
Forlag: Verlag G. Mainz
Oplagsdato: 24 maj 2019
Forfatter(e): Dr Jennifer Flohr
Forfatter(e) Dr Jennifer Flohr


Kategori Biomedicinsk teknik


ISBN-13 9783958862869


Sprog Engelsk


Indbinding Paperback


Sider 158


Udgave


Længde 11mm


Bredde 149mm


Højde 210mm


Udg. Dato 24 maj 2019


Oplagsdato 24 maj 2019


Forlag Verlag G. Mainz

Kategori sammenhænge